Sportsbook Review Opening Season Predictions: Trio of Early Week 1 Picks from NFL Week 1 Point Spreads, Totals for All 16 Games to pop up here in Las Vegas as well as in the bigger sportsbooks offshore. NFL football handicapping statistics including live NFL point spreads, NFL betting odds, wagering trends and game match-ups for See All Sportsbook Reviews. Week 3 NFL football picks - Free expert predictions against the spread and in The Rams and 49ers meet up tonight in one of the nastier looking Thursday. Here's an NFL Week 1 betting cheat sheet. Every week of the season, you will find the entire slate complete with picks against the spread, on the total and a potential Survivor Pool/straight-up selection. For an in-depth look at any matchup, click on the game graphic. NFL Vegas Odds, Betting Lines, and Point Spreads provided by 41o, Picks . first betting line received from one of our Las Vegas or Online sportsbooks. Get expert betting advice for every Week 1 game of the NFL season, check out our reviews of the top five sportsbooks, where you'll find.